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Metabolism Diazepam is N-demethylated by CYP3A4 and 2C19 to the active metabolite N-desmethyldiazepam, and is hydroxylated by CYP3A4 to the Lively metabolite temazepam.Disclaimer: This article is for information and facts only and shouldn't be employed for the prognosis or treatment method of professional medical problems. Egton Health care Informa